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Sarita Das

Sarita Das

Dr.Sarita Das

Designation: Assistant Professor

Qualification: Ph. D. in Biochemistry

Phone No.: 9040176966

ORCID: https://orcid.org/0000-0003-2153-2551

VIDWAN ID: https://vidwan.inflibnet.ac.in/profile/162089

Google Scholar ID: https://scholar.google.com/citations?hl=en&user=aOgTm_kAAAAJ

E-mail ID: sd.bot@buodisha.edu.in

Biosketch

Dr. Sarita Das received her M. Sc. degree from Khallikote Autonomous College, Berhampur, Odisha with first class first and Microbiology as specialization. She had her MPhil degree from Berhampur University with Ethnnomedicines of Odisha as her dissertation work. She qualified national level entrance examination CSIR-UGC-NET-JRF twice (Dec. 1999 and June, 2000) and also a rank holder in Life Sciences CSIR-UGC-NET, June, 2000. ...

She pursued her Ph. D. in Biochemistry at University of Madras, Chennai under the supervision of Prof. S. Niranjali Devaraj. Subsequently, she worked as a Post-Doctoral Researcher in Microbiology at University of Minnesota, USA under Prof. Paul Patrick Cleary. She also worked as a CSIR-RA. Before joining to this current position, she worked as a Lecturer in Govt. Science College, Chhtrapur. Dr. Das has expertise in Bacterial Pathogenesis and Pharmaceutical Microbiology. Her research areas focus on therapeutic importance of phytomolecules and their interference with bacterial pathogenesis, green synthesis of nanoparticles and their bactericidal activities. Her laboratory welcomes interested candidates to carry out research work in therapeutic phytomolecules and their role in bacterial pathogenesis.

  • Pharmaceutical Microbiology, Therapeutic Phytomolecules and their role in bacterial pathogenesis

Post-Doctoral Associate (USA):

  • July 2007 – Jan. 2008: Post-Doctoral Associate, Department of Microbiology, University of Minnesota, Minneapolis, USA.
  • Cloned a Streptococcal gene (DNase B), developed a his-tagged purification method for purification of DNase B protein.
  • Developed an ELISA to quantitate anti-DNase B antibody in human sera, assayed approximately 200 sera.

CSIR- Research Associate (Post-Doctoral fellow):

  • 2011 – Aug. 2013: CSIR- Research Associate, Department of Biotechnology, RIPS, Berhampur, Orissa, India.
  • Isolation of natural glycosides from Hemidesmus indicus Br. root
  • Role of natural glycosides in uropathogenesis.

Pre -Doctoral

  • June 2001 – Nov. 2004: Research work carried out at Department of Biochemistry, University of Madras, Chennai, India. (Interference of host – enteric bacterial interaction by natural products)
  • Screened anti-enterobacterial activity of indicus root extract.
  • Investigated on the inhibitory effect of indicus root extract on type III secretory system (TTSS) of Salmonellatyphimurium.
  • Identified the possible target sites of the active constituents of indicus root, role in blocking bacterial adherence, invasion and intracellular proliferation in human intestinal epithelial cell line and murine macrophage cell line.
  • Loss of bacterial virulence, pathogenicity, inflammatory activity and cell lysis as shown by immunoflourescence, transmission electron microscopy.
  • 1999 – June 2001: M.Phil. Research work carried out at Department of Botany, Khallikote Autonomous College, Berhampur, Odisha. (Ethnomedicine). Compiled 421 medicinal plants reported from Odisha state, India

  • G. students of Botany Department, Berhampur University from 18th Dec 2015 – till date.{1st Sem – Bacteria, Viruses, Fungi; 2nd Sem – Plant Physiology, Sensory and Stress biology; 3rd Sem – Plant Systematics and Environmental Biology; 4th Sem – Plant Biotechnology and Microbiology}
  • G. students of Botany Department, Govt. Science College, Chatrapur, from 4th July 2014 – 17th Dec 2015. {Cytology, Genetics, Molecular Biology, EVS, Algae, Fungi, Bryophyta, Pteridophyta, Plant Pathology, Physiology, Biochemistry)
  • G. students of Department of Biosciences, College of Pharmaceutical Sciences, under Berhampur University from Nov.2004 – Nov. 2005 {Biotechnology and Microbiology}

  • Das S, Singh PK, Ameeruddin S, Kumar Bindhani B, Obaidullah WJ, Obaidullah AJ, Mishra S and Mohapatra RK (2023), Ethnomedicinal values of Boerhaavia diffusa L. as a panacea against multiple human ailments: a state of art review. Front. Chem. 11:1297300. doi: 10.3389/fchem.2023.1297300
  • SR, Das S. In vitro antioxidant, antibiotic complementary or supplementary effects and bactericidal activities of the seeds of a weed: Hygrophila auriculata (K. Schum) Heine against uropathogens. Accepted by Int J Pharmaceu Sci Res.
  • SR, Ameeruddin. S, Pradhan NS, Das S. (2023) In vitro antioxidant, antibiotic complementing or supplementing potential and urobactericidal activity of leaf extract of Marsilea quadrifolia L.: The water fern, Res J Biotech. 18(9):120-131.
  • Sethy P, Maharana R, Ameeruddin S, Das S. (2023) Isolation of probiotics and scientific validation of using curd and salad vegetables for health benefits. Res J Berhampur Univ. 5: 52-56.
  • Dash J, Tripathy. SR, Ameeruddin. S, Das S. (2022) Ethnobotanical Study on the herbal spruce up of deities in Jagannath temple of Puri, Odisha, India: A possible step towards biodiversity conservation. Ethnobotany, 34: 35-49.
  • Das S, (2022) G1-4A, an arabinogalactan polysaccharide derived from Tinospora cordifolia (Thunb.) Miers: a natural immunomodulator. Traditional Med Res. 7(5):42.
  • Das S, Ameeruddin S. (2022) Probiotics in common urological conditions. Longhua Chinese Medicine. 5:14.
  • Das S, Sahoo BM, Bhattamisra SK. (2022) Multifunctional role of phytochemicals derived from Boerhaavia diffusa L. in human health, ailments and therapy. Current Nutrition & Food Science, 18(6): 574-588.
  • Sahoo BM, Bhattamisra SK, Das S, Tiwari A, Tiwari V, Kumar M, Singh S. (2022) Computational approach to combat COVID-19 infection: Emerging tools for accelerating drug research. Current drug discovery Tech. 19(3): 40-53.
  • Dash, K.T., Parida, B. Das, S. (2022) Phyotochemical analysis and antibacterial activity of Punica granatum L. seed extract against uropathogens. Res. J. Biotech. 17(2):31-47
  • Tripathy S. R. Dash, J. Das, S. (2021).Medico-Ethnobotanical studies of Odisha State, India for urogenital disorders : A review. TMR Integr Med, 5:e21028
  • Das, S. (2021). Therapeutic Efficacy of Roscovitine Against Cancer. In: Chakraborti, S. (eds) Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Springer, Singapore. https://doi.org/10.1007/978-981-16-1247-3_249-1
  • Das, S. (2020) Natural therapeutics for urinary tract infections – A review. Future J. of Pharmaceutical Sciences, Nature Publishing group 6:64.
  • Das, S., Prasanti, Y., Naik, P., Padhy, J.K., Panigrahi, S. (2019) Bactericidal activity of green synthesized silver nanoparticles (AgNPs) against Escherichia coli and Staphylococcus aureus. Res. J. Biotech. 14(5): 89-96.
  • Das, S. Sahoo, K.R. Parida, B. (2018) Bactericidal activity of Hemidesmus indicus R.Br. root extract against clinically isolated uropathogens. J. Med. Plant Studies 6(6): 180-192.
  • Das, S. Panigrahi, S. Panda, P. (2018) Antiurobacterial activity of Punica granatum L. seed extract. European J. Med. Plants 22(2): 1-12.
  • Das, S. Dileepan, T. Johnson, D. R. Kaplan, E. L. Cleary, P. P. (2017) Enzyme-linked immunosorbent assay for group A Streptococcal anti-DNase B in human sera, using recombinant proteins – comparison to the DNA methyl green micromethod. J. Immunol. Methods 451: 111-117.
  • Das, S. Naik, P. Panda, P. (2017) Effect of Hemidesmus indicus R.Br. root extract on urinary tract infection causing bacteria. Int. J. Herbal Med. 5(5): 160-168.
  • Das, S. Padhy J.K. and Panda P. (2017) Bioactive potential of Tridax procumbens L. leaf extract against skin infection causing bacteria. Int. J. Herbal Med. 5(3): 127-133.
  • Das, S. and Singh Bisht, S. (2013) The Bioactive and Therapeutic Potential of Hemidesmus indicus R. Br. (Indian Sarsaparilla) Root. Phytother. Res. 27: 791–801.
  • Das, S. and Devaraj, S.N. (2009) Hemidesmus indicus R. Br. root extracts reduce Salmonella typhimurium – induced inflammation in rat intestine by repressing its type three secretory proteins. J. Med. Plant Res. 3(10), 719-727.
  • Das, S. and Devaraj, S.N. (2008) Effect of Hemidesmus indicus R. Br. Root extract against Salmonella typhimurium – induced apoptosis in murine macrophage cell line (P388D1). Ind. J. Med. Res. 128, 647-657.
  • Das, S. and Devaraj, S.N. (2007) Protective role of Hemidesmus indicus R. Br. root extract against Salmonella typhimurium-induced cytotoxicity in Int 407 cell line. Phytother. Res. 21, 1209-1216.
  • Das, S. and Devaraj, S.N. (2006) Glycosides derived from Hemidesmus indicus R. Br. root inhibit adherence of Salmonella typhimurium to host cells: receptor mimicry. Phytother. Res. 20, 784-793.
  • Das, S. and Devaraj, S.N. (2006) Antienterobacterial activity of Hemidesmus indicus R.Br. root extract. Phytother. Res. 20, 416-421.
  • Das, S., Prakash, R. and Devaraj, S.N. (2003) Antidiarrhoeal effects of methanolic root extract of Hemidesmus indicus (Indian sarsaparilla) – an in vitro & in vivo study. Ind. J. Expt. Biol. 41, 363-366.
  • Das, S., Dash, S.K. and Padhy, S.N. (2003) Ethnomedicinal information’s from the tribals of Orissa    state-  J.  Hum. Eco. 14(3), 165-227.

Number of doctoral thesis supervising: 04

  • Sangita Rani Tripathy
  • Jyotirmayee Dash
  • Shaikh Ameeruddin
  • Susmita Pradhan

Number of M.Phil Dissertations supervised: 06

  • Panigrahi – Antiuropathogenic activity of Punicagranatum L. seed extract
  • Naik – Effect of Hemidesmusindicus R. Br. root extract against UTI causing bacteria
  • K. Padhy – Wound healing activity of Tridaxprocumbens L. leaf extract
  • Prasanti – Antibacterial activity of silver nanoparticles (AGNPs)
  • R. Sahoo – Bioactive potential of Hemidesmusindicus R.Br. in urinary tract infection
  • T. Dash – Effect of Punicagranatum L. seed extract against clinically isolated uropathogens

Number of M.Sc projects supervised: 17

  • Sweta Pradhan – Isolation, Characterization And Identification Of Fungal Pathogens From Rotten Fruits
  • Sripada Patro – Isolation, Characterization And Identification Of Fungal Pathogens From spoiled vegetables
  • Jyotismita Nayak –Phytochemical Analysis And Antimicrobial Study Of Andrographis paniculata
  • Abhilipsa Parhi – Antibacterial activity of Green synthesized copper nanoparticles (CuNPs)
  • Shasmita Patro – Isolation identification and characterization of endophytic microbes from Catharanthus roseus
  • Subhasmita Jena – Antibacterial activity of Green synthesized of Zinc nanoparticles (ZnNPs)
  • Arpita Kumari Behera – Isolation, identification and characterization of endophytic microbes from Adhatoda vesica
  • Rajalaxmi Maharana – Isolation of probiotic bacteria from different sources of local curds (2022)
  • Priyanka Sethi – Isolation, characterization and identification of microorganisms from fresh salad vegetables (2022)
  • Swarna Rani Panda – Bioactivity of Chromolaena odorata leave and Areca catechu nut extract clinically isolated uropathogens (2022)
  • Lipsa Panigrahi – Phytochemical analysis and antimicrobIal screening of Acacia catechu stem and resin against uropathogens (2022)
  • Jaga Bemal- Bioactivity of Boerhaavia diffusaroot extract against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa (2023)
  • Subhasini Sahoo – Phytochemical analysis and antibacterial potential of Cinnamomum tamala (Buch.-Ham.) Th.G.G.Nees leaf extract against uropathogenic bacteria (2023)
  • Debaki Behera – Isolation of lactic acid bacteria from local curd and its antibacterial activities against Escherichia coli (2023)
  • Swetashree Priyadarsini Sethy – Phytochemical analysis and antibacterial activity  of Piper longum Fruit extract against Escherichia coli and   staphylococcus aureus (2023)
  • Pratikshya Beura – Bioactive potential of Desmodium gangeticum (DC) root extract against uropathogenic bacteria (2023)
  • Subhasmita Behera- Phytochemical analysis and antibacterial potential of Cinnamomum verum Presl leaf extract against Staphylococcus aureus and Escherichia coli (2023)

Number of M.Sc projects supervising: 10

  • Diptimayee Pati
  • Rajasmita Mohapatra
  • Subhashree Subhadarshini Sahoo
  • Lizarani padna
  • Sonali Sethy
  • Sandeepta Sahu
  • Truptimayee Pradhan
  • Pragyan Padmaja
  • Sabana Khanam
  • Rojita Sahoo

  • Role of natural glycosides in antiadhesive therapy and uropathogenesis (UGC-BSR startup grant)
  • Molecular study of phytocompounds derived from Boerhaavia diffusa…uropathogenic bacteria (Department of S&T, Govt. of Odisha)

  • Microbiology
  • Plant Physiology
  • Sensory and Stress biology
  • Plant Systematics
  • Plant Pathology
  • Immunology
  • Plant Biotechnology

  • Gold medalist in M.Sc. Botany,
  • Qualified twice CSIR-UGC-NET-JRF (1999, 2000) and a Rank holder in CSIR-UGC-NET

  • CSIR (Govt. of India) funded JRF, SRF, RA Fellowship
  • NIH (USA) funded Postdoc Fellowship